Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.52 |
| ▸ | PPARA | Q07869 | 13/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713214 | 0.93 | PPARG (0.58) | PPARGPPARARAB9ANPC1PPARD | |
| SCHEMBL6722193 | 0.92 | NPC1 (0.54) | PPARGPPARAHCAR2ALDH1A1RAB9A | |
| SCHEMBL6713208 | 0.91 | GCG (0.48) | PPARGPPARAHCAR2ALDH1A1RAB9A | |
| SCHEMBL6713285 | 0.91 | PPARG (0.59) | PPARGPPARARAB9ANPC1PPARD | |
| SCHEMBL6714896 | 0.91 | PPARG (0.60) | PPARGPPARARAB9ANPC1PPARD | |
| SCHEMBL6715150 | 0.90 | HCAR2 (0.48) | PPARGPPARAHCAR2ALDH1A1RAB9A | |
| SCHEMBL6716398 | 0.86 | PPARG (0.48) | PPARGPPARAHCAR2ALDH1A1RAB9A | |
| SCHEMBL6715242 | 0.85 | PPARG (0.47) | PPARGPPARARAB9ANPC1PPARD | |
| SCHEMBL6715252 | 0.85 | PPARG (0.47) | PPARGPPARARAB9ANPC1PPARD | |
| SCHEMBL6715250 | 0.85 | PPARG (0.47) | PPARGPPARARAB9ANPC1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | SANKYO COMPANY, LTD (JP) | 2004-01-08 | — | — | US | disclosed |
| US-6528525-B1 | Amidocarboxylic acid derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-03-04 | — | — | US | disclosed |
| EP-1026149-A1 | AMIDOCARBOXYLIC ACID DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006141-A1 | Amidocarboxylic acid compounds | NR1H2, AGK, APOL1 | PPARG 23/4885PPARA 71/4885HCAR2 429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.