Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6716922 | 1.00 | MAPT (0.55) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL63804 | 0.89 | ALDH1A1 (0.52) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL5058946 | 0.88 | KMT2A (0.54) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL8661574 | 0.85 | KMT2A (0.46) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL13797719 | 0.82 | MAPT (0.50) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL13797740 | 0.82 | MAPT (0.50) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL11793556 | 0.81 | ALDH1A1 (0.64) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL5010054 | 0.80 | CYP2A6 (0.53) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL8661516 | 0.79 | ALDH1A1 (0.59) | MAPTKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL21242233 | 0.79 | MAPT (0.57) | MAPTKMT2AALDH1A1MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092574-A1 | Statin-Lp(a) inhibitor combinations | BISGAIER CHARLES LARRY (US) | 2004-05-13 | — | — | US | disclosed |
| EP-1037623-A1 | ANTIHYPERLIPIDEMIC STATIN-LP(A) INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999030706-A1 | ANTIHYPERLIPIDEMIC STATIN-LP(a) INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092574-A1 | Statin-Lp(a) inhibitor combinations | PCSK9, HMGCR, LDLR | MAPT 2011/4885KMT2A 625/4885ALDH1A1 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.