Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63804 | 0.90 | ALDH1A1 (0.52) | CYP2A6LOXL2ALDH1A1MEN1KMT2A | |
| SCHEMBL1655689 | 0.84 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL12636510 | 0.80 | PGR (0.48) | CYP2A6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL21594513 | 0.80 | ALDH1A1 (0.53) | CYP2A6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL21594521 | 0.80 | ALDH1A1 (0.53) | CYP2A6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6716916 | 0.80 | MAPT (0.55) | CYP2A6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5665672 | 0.80 | CYP19A1 (0.47) | CYP2A6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6716922 | 0.80 | MAPT (0.55) | CYP2A6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL1344068 | 0.79 | LOXL2 (0.65) | CYP2A6LOXL2SAE1UBA2ALDH1A1 | |
| SCHEMBL6802215 | 0.78 | CYP19A1 (0.58) | CYP2A6ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080311524-A1 | Method For Making Negative-Working Heat-Sensitive Lithographic Printing Plate Precursor | AGFA GRAPHICS N.V. (BE) | 2008-12-18 | — | — | US | disclosed |
| US-4251619-A | Process for forming photo-polymeric image | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1981-02-17 | — | — | US | disclosed |