SCHEMBL6719975

SCHEMBL6719975

Cc1ncnc(O)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3581232 0.81
SCHEMBL2115437 0.81
SCHEMBL3706204 0.76
SCHEMBL30229716 0.74
SCHEMBL2120002 0.74
SCHEMBL2493955 0.74
SCHEMBL31542578 0.74
SCHEMBL6718290 0.74
SCHEMBL2492265 0.72
SCHEMBL8718664 0.71 SELE (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8198858-A None JP disclosed
CN-120081829-A Pyrimidinamine compound containing pyridazinone, and preparation method and application thereof 沈阳中化农药化工研发有限公司 2025-06-03 CN disclosed
CN-119735555-A Pyrimidine-containing propylene ether compound, and preparation method and application thereof 河南大学 2025-04-01 CN disclosed
CN-119735580-A Benzopyrone compound containing pyrimidine, and preparation method and application thereof 河南大学 2025-04-01 CN disclosed
CN-115232117-B Substituted isoxazole pyrimidine amine compound, preparation method and application thereof 沈阳中化农药化工研发有限公司 2024-07-16 CN disclosed
CN-107778298-B Pyrimidine-containing substituted azole compound and application thereof 沈阳中化农药化工研发有限公司 2023-10-31 CN disclosed
CN-111004218-B Pyrimidine compound containing piperidine and application thereof 沈阳中化农药化工研发有限公司 2023-10-13 CN disclosed
EP-3760617-B1 SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) 2023-03-22 EP disclosed
CN-113512029-B Preparation and application of substituted pyrazole compound containing pyrimidinamine 沈阳中化农药化工研发有限公司 2023-01-24 CN disclosed
CN-115232117-A Substituted isoxazole pyrimidinamine compound and preparation method and application thereof 沈阳中化农药化工研发有限公司 2022-10-25 CN disclosed
US-20040092402-A1 Pyrimidine derivatives and herbicides containing the same SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) 2004-05-13 US disclosed
CN-1473155-A Pyrimidine derivatives and herbicides containing the same ס������ũҩ��ʽ���� 2004-02-04 CN disclosed
EP-1333029-A1 PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME Sumitomo Chemical Takeda Agro Company, Limited (JP) 2003-08-06 EP disclosed
EP-0708758-B1 METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED HOECHST SCHERING AGREVO GMBH (DE) 1998-02-04 EP disclosed
JP-H08198858-A PRODUCTION OF 5-CHLORO-4-HYDROXY-6-METHYLPYRIMIDINE UBE IND LTD 1996-08-06 JP disclosed
US-5523404-A Process for preparing 5-chloro-4-hydroxypyrimidines HOECHST SCHERING AGREVO GMBH (DE) 1996-06-04 US disclosed
EP-0708758-A1 METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED Hoechst Schering AgrEvo GmbH (DE) 1996-05-01 EP disclosed
WO-1995001963-A1 METHOD OF PREPARING 5-CHLORO-4-HYDROXYPYRIMIDINES, 2-CHLORENAMINES AS INTERMEDIATES IN THE METHOD, AND USE OF THE COMPOUNDS THUS PREPARED HOECHST SCHERING AGREVO GMBH (DE) 1995-01-19 WO disclosed
US-4598149-A ADRENERGIC BLOCKING AGENTS MERCK & CO., INC. (US) 1986-07-01 US disclosed
EP-0153746-A2 3-Amino-2-hydroxypropyl derivatives of pyrimidin-4-one MERCK & CO. INC. (US) 1985-09-04 EP disclosed