Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751788 | 0.84 | PIK3CG (0.38) | PIK3CGLRRK2KDM4EMEN1ALDH1A1 | |
| SCHEMBL28221737 | 0.84 | KDM4E (0.37) | LRRK2KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL13064505 | 0.75 | MAPK1 (0.41) | KDM4EALDH1A1GAA | |
| SCHEMBL8237323 | 0.74 | KCNMA1 (0.33) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL12186825 | 0.74 | LRRK2 (0.47) | LRRK2KDM4EALDH1A1GAADYRK1A | |
| SCHEMBL21048252 | 0.74 | PIK3CG (0.37) | PIK3CGLRRK2KDM4EDYRK1A | |
| SCHEMBL1109104 | 0.74 | KDM4E (0.39) | PIK3CGLRRK2KDM4EMEN1ALDH1A1 | |
| SCHEMBL12957026 | 0.74 | LRRK2 (0.43) | PIK3CGLRRK2KDM4EDYRK1ACCNA2 | |
| SCHEMBL8242596 | 0.74 | HTT (0.41) | LRRK2KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL8243678 | 0.74 | ALDH1A1 (0.41) | LRRK2KDM4EMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1333029-A1 | PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2003-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | DDX41, CBR3, DPYD | PIK3CG 2441/4885LRRK2 3256/4885UPP1 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.