Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 4/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719577 | 1.00 | IDO1 (0.41) | IDO1ALDH1A1KDM4EL3MBTL1MAPK10 | |
| SCHEMBL2773358 | 0.83 | IDO1 (0.42) | IDO1ALDH1A1L3MBTL1MAPK10HPGD | |
| SCHEMBL8783520 | 0.81 | ALDH1A1 (0.46) | IDO1ALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL17139814 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1TSHRMEN1 | |
| SCHEMBL4959620 | 0.81 | ALDH1A1 (0.46) | IDO1ALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL4714434 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1TSHRMEN1 | |
| SCHEMBL4714435 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1TSHRMEN1 | |
| SCHEMBL4959625 | 0.81 | ALDH1A1 (0.46) | IDO1ALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL15661204 | 0.81 | ALDH1A1 (0.35) | IDO1ALDH1A1L3MBTL1MAPK10HPGD | |
| SCHEMBL19071358 | 0.81 | IDO1 (0.41) | IDO1ALDH1A1L3MBTL1MAPK10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1333029-A1 | PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2003-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | DDX41, CBR3, DPYD | IDO1 1292/4885ALDH1A1 83/4885KDM4E 1493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.