Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6336780 | 0.84 | LMNA (0.49) | TSHRLMNADAOHTTPOLB | |
| SCHEMBL8985179 | 0.79 | FASN (0.46) | DAOCYP3A4FASN | |
| SCHEMBL1459291 | 0.75 | LMNA (0.49) | TSHRLMNANAAADAOPDE4D | |
| SCHEMBL1459289 | 0.75 | LMNA (0.49) | TSHRLMNANAAADAOPDE4D | |
| SCHEMBL14428814 | 0.71 | LMNA (0.43) | TSHRLMNANAAAPDE4DTAAR1 | |
| SCHEMBL18850790 | 0.71 | LMNA (0.45) | TSHRLMNANAAADAOHTT | |
| SCHEMBL8181781 | 0.69 | LMNA (0.46) | TSHRLMNANAAAPDE4DALDH1A1 | |
| SCHEMBL16464737 | 0.69 | LMNA (0.46) | TSHRLMNANAAAPDE4DALDH1A1 | |
| SCHEMBL12903277 | 0.69 | LMNA (0.49) | TSHRLMNANAAACYP3A4PTPN1 | |
| SCHEMBL18227495 | 0.69 | LMNA (0.46) | TSHRLMNANAAAPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033462-A2 | METHOD OF PREPARING (3R, 3aS, 6aR) -3- HYDROXYHEXAHYDROFURO [2, 3-b] FURAN AND RELATED COMPOUNDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2004-04-22 | — | — | WO | disclosed |