Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889741 | 0.77 | FFAR1 (0.48) | BCHE | |
| SCHEMBL8888011 | 0.74 | LTA4H (0.49) | CYP4F2CYP4A11BCHE | |
| SCHEMBL5836429 | 0.74 | ALDH1A1 (0.48) | LMNAALDH1A1TSHRBCHEACHE | |
| SCHEMBL7987732 | 0.73 | MEN1 (0.49) | LMNABCHEPPARGMEN1KMT2A | |
| SCHEMBL8888854 | 0.73 | MGLL (0.50) | CYP4F2CYP4A11BCHE | |
| SCHEMBL8890354 | 0.73 | MGLL (0.50) | CYP4F2CYP4A11BCHE | |
| SCHEMBL8888505 | 0.73 | MGLL (0.50) | CYP4F2CYP4A11BCHE | |
| SCHEMBL15239316 | 0.71 | TAAR1 (0.41) | LMNAALDH1A1TSHRNAAATAAR1 | |
| SCHEMBL1459291 | 0.71 | LMNA (0.49) | LMNAALDH1A1TSHRNAAATAAR1 | |
| SCHEMBL1459289 | 0.71 | LMNA (0.49) | LMNAALDH1A1TSHRNAAATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018745-A1 | OXAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |