Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.46 |
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 13/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28403191 | 0.82 | IDO1 (0.55) | BCHEACHECHRM2CHRM1GRIN1 | |
| SCHEMBL6230640 | 0.79 | IDO1 (0.46) | BCHEACHENPY1RNPY5RCHRM2 | |
| SCHEMBL10952345 | 0.79 | TAAR1 (0.59) | CHRM2CHRM1CYP3A4CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL11700201 | 0.78 | TAAR1 (0.58) | BCHEACHECHRM2CHRM4CHRM5 | |
| SCHEMBL79353 | 0.77 | TAAR1 (0.60) | CHRM2CHRM1CHRM3GRIN1GRIN2A | |
| SCHEMBL30118964 | 0.77 | TAAR1 (0.60) | CHRM2CHRM1CHRM3GRIN1GRIN2A | |
| SCHEMBL22838497 | 0.77 | IDO1 (0.50) | BCHEACHECHRM2CHRM1GRIN1 | |
| Biphenyl SCHEMBL8131643 | 0.75 | ALDH1A1 (0.50) | CHRM2CHRM1MEN1MAPTKMT2A | |
| SCHEMBL1546039 | 0.75 | TAAR1 (0.58) | CHRM2CHRM1 | |
| SCHEMBL21102187 | 0.74 | ALDH1A1 (0.44) | BCHEACHECHRM2CHRM1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214832-A1 | Piperazine derivative renin inhibitors | WARNER-LAMBERT COMPANY LLC | 2004-10-28 | — | — | US | disclosed |
| WO-2004089915-A1 | PIPERAZINE DERIVATIVE RENIN INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214832-A1 | Piperazine derivative renin inhibitors | REN, ACE, AGTR2 | BCHE 2129/4885ACHE 2043/4885NPY1R 2083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.