SCHEMBL6720151

SCHEMBL6720151

CC(C)(C)c1ccc(OC#N)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.47
ALDH1A1 P00352 5/20 0.47
HPGD P15428 4/20 0.47
RAB9A P51151 4/20 0.47
MAPK1 P28482 3/20 0.47
NPC1 O15118 2/20 0.47
KIF11 P52732 1/20 0.47
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
TSHR P16473 2/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
LMNA P02545 4/20 0.41
TYR P14679 1/20 0.41
NPSR1 Q6W5P4 2/20 0.40
TDP1 Q9NUW8 4/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
APP P05067 1/20 0.39
KDM4E B2RXH2 3/20 0.38
HSD17B10 Q99714 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1555244 0.86 HPGD (0.41) MAPTALDH1A1HPGDRAB9AMAPK1
SCHEMBL8909928 0.86 ALDH1A1 (0.33) MAPTALDH1A1HPGDRAB9AMAPK1
SCHEMBL140242 0.86 ESR1 (0.35) MAPTALDH1A1HPGDRAB9AMAPK1
SCHEMBL25961 0.86 HPGD (0.41) MAPTALDH1A1HPGDRAB9AMAPK1
SCHEMBL7789786 0.86 HPGD (0.41) MAPTALDH1A1HPGDRAB9AMAPK1
SCHEMBL17042662 0.86 NPC1 (0.31) MAPTALDH1A1HPGDRAB9AMAPK1
SCHEMBL24982029 0.83 NPC1 (0.31) MAPTALDH1A1HPGDRAB9AMAPK1
SCHEMBL15224863 0.83 NPC1 (0.31) MAPTALDH1A1HPGDRAB9AMAPK1
SCHEMBL20547222 0.81 KIF11 (0.42) MAPTALDH1A1HPGDRAB9AMAPK1
SCHEMBL22966431 0.81 KIF11 (0.42) MAPTALDH1A1HPGDRAB9AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698582-A1 CURABLE ORGANOSILOXANE-MODIFIED REACTION RESINS Wacker Chemie AG (DE) 2026-02-25 EP disclosed
WO-2025031588-A1 CURABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2025-02-13 WO disclosed
WO-2024217692-A1 CURABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2024-10-24 WO disclosed
WO-2024213237-A1 CURABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2024-10-17 WO disclosed
CN-116438244-B Crosslinkable organosiloxanes alkane modified reaction resins 瓦克化学股份公司 2024-08-30 CN disclosed
US-20240247107-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2024-07-25 US disclosed
EP-4153658-B1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2023-12-06 EP disclosed
US-20230272164-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2023-08-31 US disclosed
CN-116438244-A Crosslinkable organosiloxane modified reactive resins 瓦克化学股份公司 2023-07-14 CN disclosed
US-11649319-B2 Resin composition for fiber-reinforced plastic, cured product of same, and fiber-reinforced plastic comprising said cured product ADEKA CORPORATION (JP) 2023-05-16 US disclosed
US-7923516-B2 One liquid type cyanate-epoxy composite resin composition, its hardened material, manufacturing method thereof, and materials for sealing and adhesive agents using the same ADEKA CORPORATION (JP) 2011-04-12 US disclosed
US-20100210793-A1 ONE LIQUID TYPE CYANATE-EPOXY COMPOSITE RESIN COMPOSITION, ITS HARDENED MATERIAL, MANUFACTURING METHOD THEREOF, AND MATERIALS FOR SEALING AND ADHESIVE AGENTS USING THE SAME ADEKA CORPORATION (JP) 2010-08-19 US disclosed
US-20100210793-A1 ONE LIQUID TYPE CYANATE-EPOXY COMPOSITE RESIN COMPOSITION, ITS HARDENED MATERIAL, MANUFACTURING METHOD THEREOF, AND MATERIALS FOR SEALING AND ADHESIVE AGENTS USING THE SAME ADEKA CORPORATION (JP) 2010-08-19 US disclosed
US-20100204410-A1 ONE LIQUID TYPE CYANATE-EPOXY COMPOSITE RESIN COMPOSITION ADEKA CORPORATION (JP) 2010-08-12 US disclosed
US-20100204410-A1 ONE LIQUID TYPE CYANATE-EPOXY COMPOSITE RESIN COMPOSITION ADEKA CORPORATION (JP) 2010-08-12 US disclosed
US-6217943-B1 ADHESION AND REINFORCEMENT WITH SILANE CYANATE COUPLERS 3M INNOVATIVE PROPERTIES COMPANY 2001-04-17 US disclosed
US-5912377-A CONTAINING AT LEAST ONE CYANATE ESTER GROUP AND HYDROLYZABLE SILYL GROUP; REINFORCED COMPOSITES, ADESIVES, COATINGS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-06-15 US disclosed
EP-0830410-B1 AROMATIC CYANATE ESTER SILANE COUPLING AGENTS MINNESOTA MINING & MFG (US) 1999-04-07 EP disclosed
US-4820855-A IN PRESENCE OF DIALKYLTIN OXIDE CATALYST MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-04-11 US disclosed
US-4785034-A Polyolefin resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1988-11-15 US disclosed