Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938219 | 0.84 | DRD2 (0.38) | — | |
| SCHEMBL27219471 | 0.83 | CXCL8 (0.48) | NPSR1FFAR4MEN1KMT2A | |
| SCHEMBL4376769 | 0.81 | DRD2 (0.46) | LTB4RLTB4R2 | |
| SCHEMBL3721270 | 0.80 | MAPT (0.49) | NPSR1THRATHRBKEAP1FFAR1 | |
| SCHEMBL30055829 | 0.80 | FFAR1 (0.56) | NPSR1THRATHRBFFAR4KEAP1 | |
| SCHEMBL1508357 | 0.80 | FFAR1 (0.56) | NPSR1THRATHRBFFAR4KEAP1 | |
| SCHEMBL13604212 | 0.79 | DRD2 (0.46) | NPSR1 | |
| SCHEMBL2829914 | 0.79 | DRD2 (0.44) | THRATHRB | |
| SCHEMBL7369905 | 0.78 | POLB (0.53) | NPSR1KEAP1FFAR1ALDH1A1 | |
| Iodide SCHEMBL9652564 | 0.78 | DRD2 (0.44) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478619-A1 | A PROCESS FOR PREPARING A PHENYLALANINE DERIVATIVE AND INTERMEDIATES THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072536-A1 | A PROCESS FOR PREPARING A PHENYLALANINE DERIVATIVE AND INTERMEDIATES THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 2003-09-04 | — | — | WO | disclosed |
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |