Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725133 | 0.92 | LMNA (0.55) | KMT2AMEN1L3MBTL1TSHRHDAC1 | |
| SCHEMBL6725022 | 0.87 | KMT2A (0.69) | KMT2AMEN1TSHRHDAC1HDAC6 | |
| SCHEMBL6724972 | 0.82 | PPARG (0.46) | KMT2AMEN1TSHRHDAC1HDAC6 | |
| SCHEMBL8359492 | 0.80 | KMT2A (0.76) | KMT2AMEN1L3MBTL1TSHRHDAC3 | |
| SCHEMBL1003508 | 0.80 | HDAC1 (0.71) | KMT2AMEN1L3MBTL1TSHRHDAC3 | |
| SCHEMBL28778954 | 0.80 | KMT2A (0.65) | KMT2AMEN1L3MBTL1TSHRHDAC3 | |
| SCHEMBL10724882 | 0.78 | KMT2A (0.73) | KMT2AMEN1L3MBTL1TSHRHDAC3 | |
| Oxalic Acid SCHEMBL29264737 | 0.77 | HDAC1 (0.67) | KMT2AMEN1L3MBTL1TSHRHDAC3 | |
| Oxalic Acid SCHEMBL29264739 | 0.77 | HDAC1 (0.67) | KMT2AMEN1L3MBTL1TSHRHDAC3 | |
| SCHEMBL3456064 | 0.76 | KMT2A (0.70) | KMT2AMEN1L3MBTL1TSHRHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |