Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MLYCD | O95822 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6720857 | 0.87 | KMT2A (0.58) | KMT2AMEN1TSHRHDAC1HDAC6 | |
| SCHEMBL6725133 | 0.83 | LMNA (0.55) | KMT2AMEN1HPGDALDH1A1GAA | |
| SCHEMBL1003665 | 0.83 | KMT2A (0.83) | KMT2AMEN1HPGDALDH1A1GAA | |
| SCHEMBL2921609 | 0.80 | KMT2A (0.68) | KMT2AMEN1HPGDALDH1A1GAA | |
| SCHEMBL28985146 | 0.79 | KMT2A (0.71) | KMT2AMEN1HPGDALDH1A1GAA | |
| SCHEMBL20338982 | 0.78 | KMT2A (0.65) | KMT2AMEN1HPGDALDH1A1GAA | |
| SCHEMBL13229125 | 0.77 | KMT2A (0.90) | KMT2AMEN1HPGDALDH1A1GAA | |
| SCHEMBL3455399 | 0.77 | LIMK2 (0.69) | KMT2AMEN1HPGDALDH1A1GAA | |
| SCHEMBL2228587 | 0.76 | KMT2A (0.82) | KMT2AMEN1HPGDALDH1A1GAA | |
| SCHEMBL18186542 | 0.76 | KMT2A (0.82) | KMT2AMEN1HPGDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |