Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670457 | 0.81 | HSPB1 (0.51) | — | |
| SCHEMBL8977084 | 0.80 | MEN1 (0.53) | TBXA2R | |
| SCHEMBL6725208 | 0.80 | TBXA2R (0.55) | TBXA2R | |
| SCHEMBL8743939 | 0.75 | SHBG (0.52) | — | |
| SCHEMBL11240386 | 0.74 | TDP1 (0.57) | TBXA2R | |
| SCHEMBL13242050 | 0.73 | ALDH1A1 (0.50) | TBXA2R | |
| SCHEMBL15055593 | 0.72 | MAPT (0.65) | — | |
| SCHEMBL15054866 | 0.72 | HSPB1 (0.58) | TBXA2R | |
| SCHEMBL10673196 | 0.72 | TBXA2R (0.54) | TBXA2R | |
| SCHEMBL28326327 | 0.72 | HSPB1 (0.50) | TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |