Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | EP300 | Q09472 | 2/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | NEK1 | Q96PY6 | 6/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661739 | 0.81 | IDO1 (0.39) | IDO1EP300KAT2BKAT8HDAC3 | |
| SCHEMBL24819185 | 0.74 | DYRK1A (0.36) | NEK1DYRK1ATHRBTERTCYP3A4 | |
| SCHEMBL14995532 | 0.74 | DYRK1A (0.40) | NEK1DYRK1ATERTCHEK1AURKA | |
| SCHEMBL22122313 | 0.74 | IDO1 (0.33) | IDO1NEK1ALOX15 | |
| SCHEMBL911722 | 0.74 | NEK1 (0.33) | IDO1NEK1CSNK2A1 | |
| SCHEMBL3371199 | 0.69 | CYP2A6 (0.47) | IDO1HSP90AA1 | |
| SCHEMBL6233980 | 0.69 | SELL (0.45) | GAATHRBCYP3A4ALOX15HSD17B10 | |
| SCHEMBL3606665 | 0.69 | NEK1 (0.34) | IDO1NEK1DYRK1A | |
| SCHEMBL21118239 | 0.68 | ALDH1A1 (0.42) | DYRK1ATERTHSD17B10DAPK3MAP4K4 | |
| SCHEMBL9638447 | 0.67 | ADORA1 (0.40) | GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673122-B1 | CONTAINING OXIDIZER | L'ORÉAL (FR) | 2004-01-06 | — | — | US | claimed |
| EP-0861835-B1 | Para-aminophenols containing compositions for dyeing of keratin fibres, dyeing process, para-aminophenols and a method for their preparation | OREAL (FR) | 2002-04-17 | — | — | EP | claimed |
| US-6203580-B1 | OXIDATIVE DYEING | L'OREAL (FR) | 2001-03-20 | — | — | US | claimed |
| EP-0861835-A1 | Para-aminophenols containing compositions for dyeing of keratin fibres, dyeing process, para-aminophenols and a method for their preparation | L'OREAL (FR) | 1998-09-02 | — | — | EP | claimed |
| US-6673122-B1 | CONTAINING OXIDIZER | L'ORÉAL (FR) | 2004-01-06 | — | — | US | disclosed |
| EP-0861835-B1 | Para-aminophenols containing compositions for dyeing of keratin fibres, dyeing process, para-aminophenols and a method for their preparation | OREAL (FR) | 2002-04-17 | — | — | EP | disclosed |
| US-6203580-B1 | OXIDATIVE DYEING | L'OREAL (FR) | 2001-03-20 | — | — | US | disclosed |
| EP-0861835-A1 | Para-aminophenols containing compositions for dyeing of keratin fibres, dyeing process, para-aminophenols and a method for their preparation | L'OREAL (FR) | 1998-09-02 | — | — | EP | disclosed |