Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.59 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5303103 | 0.87 | TTR (0.52) | GABRA1GABRB1EYA3CYP2C19MEN1 | |
| SCHEMBL6732706 | 0.83 | TPMT (0.46) | GABRA1GABRB1ALDH1A1EYA3CYP2C19 | |
| SCHEMBL6720720 | 0.83 | LMNA (0.62) | ALDH1A1TDP1L3MBTL1EYA3CYP2C19 | |
| SCHEMBL6725029 | 0.82 | VCAM1 (0.56) | ALDH1A1TDP1MEN1KMT2ALMNA | |
| SCHEMBL24419784 | 0.82 | ALDH1A1 (0.64) | ALDH1A1EYA3CYP2C19SRD5A2LMNA | |
| SCHEMBL1602430 | 0.80 | ATM (0.57) | ALDH1A1ATMTDP1L3MBTL1EYA3 | |
| SCHEMBL6723795 | 0.80 | TTR (0.51) | ALDH1A1ATMTDP1EYA3CYP2C19 | |
| SCHEMBL31255439 | 0.80 | CNR2 (0.57) | GABRA1GABRB1ALDH1A1ATMTDP1 | |
| SCHEMBL3349765 | 0.79 | ATM (0.84) | GABRA1GABRB1ALDH1A1ATMTDP1 | |
| SCHEMBL13045507 | 0.79 | ATM (0.84) | GABRA1GABRB1ALDH1A1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |
| US-6063815-A | TREATMENT OF METABOLIC DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-05-16 | — | — | US | disclosed |