Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1E | P28566 | 3/20 | 0.63 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12531975 | 1.00 | HTR1E (0.63) | HTR1ES1PR3LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11526873 | 0.98 | HTR1E (0.61) | HTR1ES1PR3LMNAMEN1KMT2A | |
| SCHEMBL28622389 | 0.98 | HTR1E (0.65) | HTR1ES1PR3LMNAMEN1KMT2A | |
| SCHEMBL69127 | 0.98 | HTR1E (0.65) | HTR1ES1PR3LMNAMEN1KMT2A | |
| SCHEMBL67619 | 0.94 | HTR1E (0.60) | HTR1ES1PR3LMNAMEN1KMT2A | |
| SCHEMBL66920 | 0.90 | LMNA (0.54) | HTR1ES1PR3LMNAMEN1KMT2A | |
| SCHEMBL4461851 | 0.90 | HTR1E (0.53) | HTR1ES1PR3LMNAMEN1KMT2A | |
| SCHEMBL193456 | 0.89 | HTR1E (0.63) | HTR1ES1PR3LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11359974 | 0.88 | LMNA (0.53) | HTR1ES1PR3LMNAMEN1KMT2A | |
| SCHEMBL9780781 | 0.87 | HTR1E (0.61) | HTR1ES1PR3LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836081-A | Ether epoxy toughening agent and preparation method and application thereof | 中国林业科学研究院林产化学工业研究所 | 2023-10-03 | — | — | CN | claimed |
| EP-2718281-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMA SPA (IT) | 2015-09-09 | — | — | EP | claimed |
| CN-1750820-A | Thiazole and oxazole derivatives which modulate PPAR activity | WARNER LAMBERT CO (US) | 2006-03-22 | — | — | CN | claimed |
| EP-0234400-A1 | Esters of N-alkyl-nortropines and their quaternary derivatives having anti-bronchospastic activity, process for their preparation and pharmaceutical compositions containing them | Laboratori Guidotti S.p.A. (IT) | 1987-09-02 | — | — | EP | claimed |
| EP-4249470-B1 | METHOD FOR PREPARING ALPHA-AMINO ACIDS | PHILIPPS UNIV MARBURG (DE) | 2024-11-13 | — | — | EP | disclosed |
| EP-4332089-A1 | METHOD FOR PREPARING AMINO ACIDS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2024-03-06 | — | — | EP | disclosed |
| CN-117285439-A | Phenylalanine amide derivatives as beta 2 Use of allosteric antagonists of adrenergic receptors | 常州大学 | 2023-12-26 | — | — | CN | disclosed |
| CN-116836081-A | Ether epoxy toughening agent and preparation method and application thereof | 中国林业科学研究院林产化学工业研究所 | 2023-10-03 | — | — | CN | disclosed |
| EP-4249470-A1 | METHOD FOR PREPARING ALPHA-AMINO ACIDS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2023-09-27 | — | — | EP | disclosed |
| EP-2800738-B1 | HETEROCYCLIC COMPOUNDS AND METHODS FOR THEIR USE | NOVARTIS AG (CH) | 2020-04-08 | — | — | EP | disclosed |
| EP-3288527-B1 | N-ARALKYLCARBONYLDIAMINE COMPOUNDS AND PERSONAL CARE COMPOSITIONS COMPRISING THE SAME | UNILEVER PLC A COMPANY REGISTERED IN ENGLAND AND WALES UNDER COMPANY NO 41424 OF (GB) | 2020-02-19 | — | — | EP | disclosed |
| CN-107011229-B | The application method of heterocyclic compound and they | 诺华股份有限公司 | 2019-11-05 | — | — | CN | disclosed |
| US-4454338-A | 6-AMIDINO-2-NATHTHYL-4-GUANIDINOBENZOATE | TORII & CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |
| EP-0048433-A2 | Novel amidine compounds, process for producing same and anti-complement agent comprising them | TORII & CO., LTD. (JP) | 1982-03-31 | — | — | EP | disclosed |
| US-4247597-A | Electroscopic carrier particles having a carboxylic acid surface treatment | PITNEY BOWES, INC. (US) | 1981-01-27 | — | — | US | disclosed |
| EP-0001503-B1 | ANTITHROMBOTIC COMPOSITIONS CONTAINING BENZISOTHIAZOLONES | BEECHAM GROUP PLC (GB) | 1981-01-07 | — | — | EP | disclosed |
| EP-0001503-A1 | Antithrombotic compositions containing benzisothiazolones | BEECHAM GROUP PLC (GB) | 1979-04-18 | — | — | EP | disclosed |
| US-4021478-A | Preparation of carboxylic acids from glycidonitriles with ionic lewis acids | THE UPJOHN COMPANY (US) | 1977-05-03 | — | — | US | disclosed |
| US-3994964-A | Processes for the production of carboxylic acids from glycidonitriles | THE UPJOHN COMPANY (US) | 1976-11-30 | — | — | US | disclosed |
| US-3975431-A | Preparing carboxylic acids from glycidonitriles through enol acylates | THE UPJOHN COMPANY (US) | 1976-08-17 | — | — | US | disclosed |