Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650668 | 0.82 | ALDH1A1 (0.61) | MAPTALDH1A1GAACYP3A4ALOX15 | |
| SCHEMBL30823445 | 0.82 | CYP3A4 (0.52) | MAPTALDH1A1GAACYP3A4ALOX15 | |
| SCHEMBL2049441 | 0.82 | CYP3A4 (0.52) | MAPTALDH1A1GAACYP3A4ALOX15 | |
| SCHEMBL7289170 | 0.82 | ALDH1A1 (0.56) | MAPTALDH1A1GAACYP3A4ALOX15 | |
| SCHEMBL67759 | 0.82 | CYP3A4 (0.52) | MAPTALDH1A1GAACYP3A4ALOX15 | |
| SCHEMBL11038441 | 0.80 | ALDH1A1 (0.48) | MAPTALDH1A1GAACYP3A4ALOX15 | |
| SCHEMBL212921 | 0.80 | HSD17B10 (0.55) | MAPTALDH1A1GAACYP3A4ALOX15 | |
| SCHEMBL14283744 | 0.80 | MAPT (0.48) | MAPTALDH1A1GAACYP3A4ALOX15 | |
| SCHEMBL24316945 | 0.77 | CYP3A4 (0.52) | MAPTALDH1A1GAACYP3A4ALOX15 | |
| Dichloroxylenol SCHEMBL574277 | 0.77 | ALDH1A1 (0.61) | MAPTALDH1A1GAACYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673550-B2 | PROBES FOR USE IN THE DETECTION AND MEASUREMENT OF PREFERENTIAL COMPOUND IN SAMPLE | ACLARA BIOSCIENCES, INC. | 2004-01-06 | — | — | US | disclosed |
| US-3988318-A | HYDROXY-PHENOLS; PLASTICIZERS | GAF CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |