Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589114 | 0.91 | LMNA (0.36) | LMNATHRB | |
| SCHEMBL1558945 | 0.90 | LMNA (0.33) | LMNA | |
| SCHEMBL1559823 | 0.87 | LMNA (0.32) | LMNA | |
| SCHEMBL1558248 | 0.85 | LMNA (0.32) | LMNA | |
| SCHEMBL15352117 | 0.84 | LMNA (0.36) | LMNATHRB | |
| SCHEMBL6358198 | 0.84 | LMNA (0.36) | LMNATHRB | |
| SCHEMBL11817616 | 0.84 | LMNA (0.36) | LMNATHRB | |
| SCHEMBL18130241 | 0.84 | LMNA (0.36) | LMNATHRB | |
| SCHEMBL31355115 | 0.82 | LMNA (0.35) | LMNA | |
| SCHEMBL674119 | 0.82 | THRB (0.31) | LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9156938-B2 | Compositions, methods, and systems comprising fluorous-soluble polymers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-10-13 | — | — | US | disclosed |
| US-20120177578-A1 | COMPOSITIONS, METHODS, AND SYSTEMS COMPRISING FLUOROUS-SOLUBLE POLYMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-07-12 | — | — | US | disclosed |
| WO-2012024592-A2 | COMPOSITIONS, METHODS, AND SYSTEMS COMPRISING FLUOROUS-SOLUBLE POLYMERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120177578-A1 | COMPOSITIONS, METHODS, AND SYSTEMS COMPRISING FLUOROUS-SOLUBLE POLYMERS | NAF1, PFAS, MALT1 | LMNA 1126/4885THRB 3638/4885CA2 3148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.