Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951460 | 0.85 | KEAP1 (0.42) | KEAP1NFE2L2SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6719659 | 0.81 | GAA (0.45) | SMN1; SMN2TSHRALDH1A1POLBAPEX1 | |
| SCHEMBL979056 | 0.80 | KEAP1 (0.55) | KEAP1NFE2L2SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL32668944 | 0.80 | KEAP1 (0.55) | KEAP1NFE2L2SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL23899317 | 0.79 | KDM4E (0.41) | KEAP1NFE2L2MEN1KMT2ATDP1 | |
| SCHEMBL364382 | 0.78 | KEAP1 (0.48) | KEAP1NFE2L2SMN1; SMN2TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL9488278 | 0.78 | KEAP1 (0.53) | KEAP1NFE2L2SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL6740271 | 0.77 | LMNA (0.44) | SMN1; SMN2ALDH1A1POLBAPEX1HPGD | |
| SCHEMBL7007499 | 0.77 | KEAP1 (0.44) | KEAP1NFE2L2SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL25170326 | 0.76 | KDM1A (0.35) | SMN1; SMN2TSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1333029-A1 | PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2003-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092402-A1 | Pyrimidine derivatives and herbicides containing the same | DDX41, CBR3, DPYD | KEAP1 157/4885NFE2L2 1862/4885SMN1; SMN2 4090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.