Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.63 |
| ▸ | ALB | P02768 | 2/20 | 0.63 |
| ▸ | MMP3 | P08254 | 1/20 | 0.57 |
| ▸ | KIF11 | P52732 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785846 | 0.93 | TTR (0.55) | TTRALBMMP3KIF11CA12 | |
| SCHEMBL2786381 | 0.88 | KIF11 (0.49) | TTRALBMMP3KIF11CA12 | |
| SCHEMBL2785702 | 0.82 | MMP3 (0.55) | TTRALBMMP3KIF11CA12 | |
| SCHEMBL13368942 | 0.78 | KIF11 (0.46) | TTRALBMMP3KIF11CA12 | |
| SCHEMBL31757686 | 0.78 | KIF11 (0.46) | TTRALBMMP3KIF11CA12 | |
| SCHEMBL19993388 | 0.78 | MMP3 (0.45) | TTRALBMMP3KIF11CA12 | |
| Ioxynil SCHEMBL1701373 | 0.78 | TTR (1.00) | TTRALBMMP3CA12CA2 | |
| Ioxynil SCHEMBL39616 | 0.78 | TTR (1.00) | TTRALBMMP3CA12CA2 | |
| SCHEMBL7125883 | 0.78 | MMP3 (0.66) | TTRALBMMP3KIF11CA12 | |
| SCHEMBL16789941 | 0.78 | MMP3 (0.64) | MMP3KIF11CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |