Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 8/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630236 | 0.90 | NOS1 (0.43) | IDO1NOS1TDP1L3MBTL1 | |
| SCHEMBL6441713 | 0.82 | NOS1 (0.48) | IDO1NOS1TDP1AKT1ALDH1A1 | |
| SCHEMBL16116290 | 0.80 | IDO1 (0.48) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL20109346 | 0.79 | IDO1 (0.44) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL7125566 | 0.79 | IDO1 (0.52) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL10752204 | 0.79 | KDM4E (0.47) | IDO1TDP1CYP1A2ALDH1A1CYP3A4 | |
| Acrylic Acid SCHEMBL27494455 | 0.78 | CYP2C19 (0.55) | IDO1NOS3NOS1NOS2CYP2C19 | |
| SCHEMBL28774870 | 0.77 | IDO1 (0.46) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL27679236 | 0.77 | IDO1 (0.46) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL16115015 | 0.77 | IDO1 (0.54) | IDO1NOS3NOS1NOS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022496-A | Chromene compound | TOKUYAMA CORPORATION (JP) | 2000-02-08 | — | — | US | claimed |
| CN-114929455-B | Inkjet method for producing spectacle lenses | 卡尔蔡司光学国际有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-114929455-A | Ink jet method for producing spectacle lenses | 卡尔蔡司光学国际有限公司 | 2022-08-19 | — | — | CN | disclosed |
| WO-2021140248-A1 | INKJET METHOD FOR PRODUCING A SPECTACLE LENS | CARL ZEISS VISION INTERNATIONAL GMBH (DE) | 2021-07-15 | — | — | WO | disclosed |
| US-10633403-B2 | N-heterocyclic phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA (US) | 2020-04-28 | — | — | US | disclosed |
| EP-2966102-B1 | CURABLE PHOTOCHROMIC COMPOSITION, CURED PRODUCT THEREOF, AND LAMINATE INCLUDING CURED PRODUCT | TOKUYAMA CORP (JP) | 2019-03-27 | — | — | EP | disclosed |
| US-20180118770-A1 | N-Heterocyclic Phosphines | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2018-05-03 | — | — | US | disclosed |
| US-9890324-B2 | Photochromic curable composition, cured product thereof and laminate including the cured product | TOKUYAMA CORPORATION (JP) | 2018-02-13 | — | — | US | disclosed |
| US-9873819-B2 | Curable composition and photochromic composition | TOKUYAMA CORPORATION (JP) | 2018-01-23 | — | — | US | disclosed |
| US-20170210943-A1 | CURABLE COMPOSITION AND PHOTOCHROMIC COMPOSITION | TOKUYAMA CORPORATION (JP) | 2017-07-27 | — | — | US | disclosed |
| EP-0875509-B1 | Chromene compound | TOKUYAMA CORP (JP) | 2001-06-20 | — | — | EP | disclosed |
| EP-1054010-A1 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2000-11-22 | — | — | EP | disclosed |
| US-6141135-A | Photochromic composition | TOKUYAMA CORPORATION (JP) | 2000-10-31 | — | — | US | disclosed |
| US-6022496-A | Chromene compound | TOKUYAMA CORPORATION (JP) | 2000-02-08 | — | — | US | disclosed |
| EP-0965628-A1 | Photochromic composition | TOKUYAMA CORPORATION (JP) | 1999-12-22 | — | — | EP | disclosed |
| US-5932725-A | PHOTOCHROMIC; E.G., 3,3-BIS(3-FLUORO-4-METHOXYPHENYL)-6-MORPHOLINO-3H-BENZO(F)-CHR OMENE | TOKUYAMA CORPORATION (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0875509-A1 | Chromene compound | TOKUYAMA CORPORATION (JP) | 1998-11-04 | — | — | EP | disclosed |
| US-4710557-A | Polymers of thiophenyl thioacrylate and thiomethacrylate monomers | EASTMAN KODAK COMPANY (US) | 1987-12-01 | — | — | US | disclosed |
| EP-0198572-A1 | Thiophenyl thioacrylate and thiomethacrylate monomers, methods of preparing said monomers, intermediates, polymers thereof and optical components containing said polymers | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-10-22 | — | — | EP | disclosed |
| US-4606864-A | Thiophenyl thioacrylate and thiomethacrylate monomers | EASTMAN KODAK COMPANY (US) | 1986-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118770-A1 | N-Heterocyclic Phosphines | NANP, PPIP5K2, PHPT1 | IDO1 3933/4885NOS3 956/4885NOS1 1015/4885 |
| US-10633403-B2 | N-heterocyclic phosphines | NANP, PPIP5K2, PHPT1 | IDO1 3933/4885NOS3 956/4885NOS1 1015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.