Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 9/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23630237 | 0.90 | NOS1 (0.40) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL16116290 | 0.85 | IDO1 (0.48) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL672394 | 0.77 | IDO1 (0.48) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL3077760 | 0.76 | NPC1 (0.51) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL3077763 | 0.76 | NPC1 (0.51) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL28774870 | 0.74 | IDO1 (0.46) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL42484 | 0.74 | IDO1 (0.54) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL28309376 | 0.74 | IDO1 (0.40) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL3070200 | 0.73 | IDO1 (0.71) | IDO1NOS3NOS1NOS2TDP1 | |
| SCHEMBL79058 | 0.73 | IDO1 (0.58) | IDO1NOS3NOS1NOS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101006114-B | Polymerisable composition containing an odour masking agent and a perfume, an optical lens and a production method | ESSILOR INT | 2011-09-21 | — | — | CN | disclosed |
| CN-101006114-A | Polymerisable composition containing an odour masking agent and a perfume, an optical lens and a production method | ESSILOR INT (FR) | 2007-07-25 | — | — | CN | disclosed |