Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.49 |
| ▸ | ITGAL | P20701 | 4/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 4/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6551537 | 1.00 | OPRM1 (0.50) | OPRM1OPRL1ITGB2ICAM1ITGAL | |
| Hydrochloric Acid SCHEMBL6727142 | 0.99 | OPRM1 (0.49) | OPRM1OPRL1ITGB2ICAM1ITGAL | |
| Hydrochloric Acid SCHEMBL6727141 | 0.99 | OPRM1 (0.49) | OPRM1OPRL1ITGB2ICAM1ITGAL | |
| SCHEMBL5164867 | 0.92 | KMT2A (0.48) | OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL5164853 | 0.91 | KMT2A (0.47) | OPRM1OPRL1 | |
| SCHEMBL5163884 | 0.88 | OPRL1 (0.65) | OPRM1OPRL1ITGB2ICAM1ITGAL | |
| SCHEMBL6551984 | 0.88 | OPRL1 (0.65) | OPRM1OPRL1ITGB2ICAM1ITGAL | |
| SCHEMBL6729772 | 0.88 | OPRL1 (0.65) | OPRM1OPRL1ITGB2ICAM1ITGAL | |
| Hydrochloric Acid SCHEMBL6729807 | 0.87 | OPRL1 (0.64) | OPRM1OPRL1ITGB2ICAM1ITGAL | |
| Hydrochloric Acid SCHEMBL6729815 | 0.87 | OPRL1 (0.64) | OPRM1OPRL1ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229872-A1 | Substituted cyclohexane-1,4-diamine compounds with anti-diarrhea and peripheral analgesic activity | GRUENENTHAL GMBH (DE) | 2004-11-18 | — | — | US | claimed |
| US-20040229872-A1 | Substituted cyclohexane-1,4-diamine compounds with anti-diarrhea and peripheral analgesic activity | GRUENENTHAL GMBH (DE) | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229872-A1 | Substituted cyclohexane-1,4-diamine compounds with anti-diarrhea and peripheral analgesic activity | ARG1, CD2, PDCD1 | OPRM1 250/4885OPRL1 41/4885ITGB2 2197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.