Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7049426 | 0.71 | BCHE (0.65) | MAPTHPGDKDM4EALDH1A1NPSR1 | |
| SCHEMBL14527638 | 0.70 | FYN (0.47) | MAPTHPGDKDM4EALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL8059101 | 0.70 | BCHE (0.63) | MAPTHPGDKDM4EALDH1A1NPSR1 | |
| SCHEMBL10146654 | 0.69 | MAPT (0.50) | MAPTHPGDKDM4EALDH1A1NPSR1 | |
| SCHEMBL5172582 | 0.68 | GAA (0.41) | MAPTHPGDKDM4EALDH1A1NPSR1 | |
| SCHEMBL6974958 | 0.68 | FYN (0.55) | HPGDKDM4EALDH1A1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5172286 | 0.68 | GAA (0.41) | MAPTHPGDKDM4EALDH1A1NPSR1 | |
| SCHEMBL2232345 | 0.67 | CYP1A1 (0.62) | HPGDALDH1A1LMNAL3MBTL1GAA | |
| SCHEMBL8022641 | 0.67 | ACHE (0.81) | KDM4EALDH1A1LMNAGAAACHE | |
| SCHEMBL14523886 | 0.67 | KDM4E (0.76) | MAPTHPGDKDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040034051-A1 | PHENANTHRIDINE DERIVATIVES AND ANTITUMORAL MEDICAMENTS CONTAINING PHENANTHRIDINE | CLEMENT BERND (DE) | 2004-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034051-A1 | PHENANTHRIDINE DERIVATIVES AND ANTITUMORAL MEDICAMENTS CONTAINING PHENANTHRIDINE | VHL, ENTPD5, SLC30A5 | MAPT 3727/4885HPGD 460/4885KDM4E 2607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.