Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.81 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | BCHE | P06276 | 7/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492556 | 0.77 | ACHE (1.00) | ACHEBCHEALDH1A1KDM4E | |
| SCHEMBL8810684 | 0.73 | ACHE (0.66) | ACHEBCHEALDH1A1KDM4ELMNA | |
| SCHEMBL6491511 | 0.72 | BCHE (1.00) | ACHEBCHEALDH1A1KDM4ELMNA | |
| SCHEMBL27854357 | 0.72 | ADORA2A (0.56) | ACHENPC1RAB9AADORA2AALDH1A1 | |
| SCHEMBL11057340 | 0.71 | DCPS (0.57) | ACHENPC1RAB9AADORA2AALDH1A1 | |
| SCHEMBL11059950 | 0.71 | NQO2 (0.59) | ACHENPC1RAB9AADORA2AALDH1A1 | |
| SCHEMBL6883498 | 0.70 | ADORA1 (0.54) | ACHENPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL12043418 | 0.70 | ACHE (1.00) | ACHEBCHEADORA2A | |
| SCHEMBL8005649 | 0.69 | ACHE (0.78) | ACHEBCHEALDH1A1KDM4E | |
| SCHEMBL6724474 | 0.67 | MAPT (0.46) | ACHENPC1RAB9AADORA2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130228-A | Polycyclic compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2000-10-10 | — | — | US | disclosed |