Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.44 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.41 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | FURIN | P09958 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5302657 | 0.84 | PRSS1 (0.44) | PRSS1PRSS2PRSS3TMPRSS15F2 | |
| SCHEMBL6724722 | 0.78 | PRSS1 (0.59) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL7475217 | 0.76 | PRSS1 (0.53) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL10435021 | 0.76 | KMT2A (0.47) | PKM | |
| SCHEMBL112115 | 0.75 | PRSS1 (0.51) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL1819034 | 0.73 | POLB (0.52) | PRSS1PRSS2PRSS3TMPRSS15F2 | |
| SCHEMBL9295361 | 0.73 | PRSS1 (0.49) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL2535426 | 0.70 | PRSS1 (0.59) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL19486253 | 0.70 | SMN1; SMN2 (0.58) | PRSS1PRSS2PRSS3TMPRSS15F2 | |
| SCHEMBL19489229 | 0.70 | SMN1; SMN2 (0.58) | PRSS1PRSS2PRSS3TMPRSS15F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673756-B2 | MULTILAYER; CUTTING, JOINING UNDER PRESSURE | SYMRISE GMBH & CO. KG (DE) | 2004-01-06 | — | — | US | disclosed |
| US-20020173436-A1 | Multilayer; cutting, joining under pressure | SYMRISE GMBH & CO. KG (DE) | 2002-11-21 | — | — | US | disclosed |