Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4765648 | 0.83 | MAPT (0.43) | SMN1; SMN2LMNAMAPTKMT2ACYP1A2 | |
| SCHEMBL4772149 | 0.80 | HRH4 (0.56) | SMN1; SMN2LMNAMAPTKMT2ACYP1A2 | |
| SCHEMBL4769857 | 0.79 | NTSR1 (0.47) | SMN1; SMN2LMNAMAPTKMT2ACYP1A2 | |
| SCHEMBL4775573 | 0.79 | PRMT5 (0.46) | SMN1; SMN2LMNAMAPTKMT2ACYP1A2 | |
| Oxalic Acid SCHEMBL4769392 | 0.79 | MCHR1 (0.47) | SMN1; SMN2LMNAMAPTKMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL4769084 | 0.78 | PRMT5 (0.45) | SMN1; SMN2LMNAMAPTKMT2ACYP1A2 | |
| SCHEMBL4763521 | 0.78 | SMPD1 (0.43) | SMN1; SMN2KMT2ACYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL4772199 | 0.77 | KMT2A (0.54) | SMN1; SMN2LMNAMAPTKMT2ACYP1A2 | |
| SCHEMBL4763429 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAMAPTKMT2ACYP1A2 | |
| SCHEMBL4770137 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAMAPTKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | MUSK, HTR1A, RYR1 | SMN1; SMN2 37/4885LMNA 1917/4885MAPT 3756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.