Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6728507 | 0.80 | MEN1 (0.49) | NSD2ALDH1A1L3MBTL1MEN1HPGD | |
| SCHEMBL6820149 | 0.80 | MEN1 (0.43) | NSD2ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL6725779 | 0.76 | KMT2A (0.64) | ESR1SMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL28238266 | 0.73 | ELANE (0.51) | SMN1; SMN2ALDH1A1L3MBTL1MEN1HPGD | |
| SCHEMBL28547817 | 0.73 | KMT2A (0.49) | ESR1SMN1; SMN2ALDH1A1ESR2L3MBTL1 | |
| SCHEMBL2907355 | 0.73 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1L3MBTL1MEN1HPGD | |
| SCHEMBL17854061 | 0.72 | ESR1 (0.66) | ESR1SERPINE1L3MBTL1 | |
| SCHEMBL17836970 | 0.72 | ESR1 (0.77) | ESR1TYRSERPINE1ALDH1A1L3MBTL1 | |
| SCHEMBL17873233 | 0.72 | ESR1 (0.77) | ESR1TYRSERPINE1ALDH1A1L3MBTL1 | |
| SCHEMBL6723785 | 0.72 | MAOB (0.54) | SMN1; SMN2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2003009871-A2 | INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR FOR DECREASING BODY MASS | GENSET S.A. (FR) | 2003-02-06 | — | — | WO | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |