Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725272 | 1.00 | KDM4E (0.40) | KDM4ESMN1; SMN2LMNAPSMB5L3MBTL1 | |
| SCHEMBL10315354 | 0.88 | ATR (0.47) | KDM4ESMN1; SMN2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL10315097 | 0.88 | ATR (0.47) | KDM4ESMN1; SMN2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL6725532 | 0.88 | PSMB5 (0.44) | KDM4ESMN1; SMN2LMNAPSMB5L3MBTL1 | |
| SCHEMBL6725518 | 0.88 | PSMB5 (0.44) | KDM4ESMN1; SMN2LMNAPSMB5L3MBTL1 | |
| SCHEMBL12146794 | 0.87 | PSMB5 (0.49) | KDM4ESMN1; SMN2LMNAPSMB5L3MBTL1 | |
| SCHEMBL12690525 | 0.87 | L3MBTL1 (0.38) | KDM4ELMNAPSMB5L3MBTL1ALDH1A1 | |
| SCHEMBL12146605 | 0.86 | L3MBTL1 (0.46) | KDM4ESMN1; SMN2LMNAPSMB5L3MBTL1 | |
| SCHEMBL6726086 | 0.86 | PSMB5 (0.48) | KDM4ESMN1; SMN2LMNAPSMB5L3MBTL1 | |
| SCHEMBL6725426 | 0.86 | PSMB5 (0.48) | KDM4ESMN1; SMN2LMNAPSMB5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178216-B2 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-8178216-B2 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20090072718-A1 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-03-19 | — | — | US | disclosed |
| US-20090072718-A1 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090072718-A1 | Quinoxaline derivative, and light-emitting element, light-emitting device, and electronic device including quinoxaline derivative | CRY1, GRK1, CRY2 | KDM4E 2006/4885SMN1; SMN2 4328/4885LMNA 3498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.