SCHEMBL6725451

SCHEMBL6725451

O=C(c1ncc(-c2cc[n+]([O-])cc2)cn1)N1CCN(S(=O)(=O)N2Cc3ccc(Cl)cc3C2)CC1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
F10 P00742 5/20 0.36
FNTA P49354 12/20 0.34
FNTB P49356 12/20 0.34
LMNA P02545 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
DPP4 P27487 1/20 0.33
FAP Q12884 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6726691 0.88 F10 (0.38) F10LMNAL3MBTL1POLB
SCHEMBL6725145 0.86 F10 (0.44) F10LMNAL3MBTL1MEN1POLB
SCHEMBL6735703 0.83 LSS (0.47) F10FNTAFNTBLMNAL3MBTL1
SCHEMBL6725445 0.82 F10 (0.35) F10LMNAL3MBTL1
SCHEMBL6734044 0.81 LMNA (0.42) LMNAL3MBTL1MEN1POLBKMT2A
SCHEMBL6734093 0.80 F10 (0.49) F10LMNA
SCHEMBL6735702 0.77 F10 (0.41) F10FNTAFNTBLMNAL3MBTL1
SCHEMBL6730261 0.76 ALDH1A1 (0.36) F10LMNAL3MBTL1MEN1KMT2A
SCHEMBL6725819 0.76 F10 (0.56) F10
SCHEMBL6730258 0.76 ALDH1A1 (0.36) F10LMNAL3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction F2, CYC1, SULT2A1 F10 19/4885FNTA 2112/4885FNTB 1488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.