Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | GABRE | P78334 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926198 | 0.83 | CA1 (0.38) | NOTUMTSHRSMN1; SMN2RXRARXRB | |
| SCHEMBL5508917 | 0.79 | CA1 (0.40) | DPP4KEAP1NFE2L2POLBAPEX1 | |
| SCHEMBL6726442 | 0.79 | SOS1 (0.38) | TSHRSMN1; SMN2RXRARXRBRXRG | |
| SCHEMBL2926338 | 0.76 | NOTUM (0.38) | DPP4MRGPRX4GABRPGABRDGABRA1 | |
| SCHEMBL6728940 | 0.75 | AKR1C2 (0.37) | DPP4KEAP1NFE2L2POLBAPEX1 | |
| SCHEMBL8926676 | 0.74 | CA1 (0.36) | TSHRSMN1; SMN2CA1CA2CA4 | |
| SCHEMBL22115216 | 0.72 | SMN1; SMN2 (0.44) | TSHRSMN1; SMN2RXRARXRBRXRG | |
| SCHEMBL31446281 | 0.72 | CA1 (0.42) | KEAP1NFE2L2NOTUMTSHRSMN1; SMN2 | |
| SCHEMBL9769391 | 0.71 | HSD17B10 (0.39) | KEAP1TSHRSMN1; SMN2RXRARXRB | |
| SCHEMBL320103 | 0.71 | GABRP (0.48) | DPP4TLR7MRGPRX4GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677479-B2 | REACTING A HALOGENATED BENZENE COMPOUND WITH ALDEHYDE; SOLVENT EXTRACTION; PURIFICATION | CLARIANT FINANCE LBVI LIMITED (VG) | 2004-01-13 | — | — | US | disclosed |
| US-20030092930-A1 | Substituted fluoroaromatics, process for preparing them and their use | CLARIANT GMBH | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092930-A1 | Substituted fluoroaromatics, process for preparing them and their use | CYP2F1, CYP1A1, CYP4X1 | DPP4 4490/4885KEAP1 496/4885NFE2L2 714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.