Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725139 | 0.81 | FFAR1 (0.33) | ALDH1A1HSD17B10FFAR4FFAR1EPHX2 | |
| SCHEMBL10974680 | 0.77 | EPHX2 (0.34) | FFAR4FFAR1EPHX2 | |
| SCHEMBL5508917 | 0.75 | CA1 (0.40) | KDM4EALDH1A1HSD17B10KMOPOLB | |
| SCHEMBL6725463 | 0.75 | DPP4 (0.33) | AKR1C2AKR1C1KMOMRGPRX4POLB | |
| SCHEMBL10977611 | 0.75 | EPHX2 (0.35) | FFAR4FFAR1EPHX2 | |
| SCHEMBL6725020 | 0.72 | KMO (0.43) | AKR1C2AKR1C1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL6723631 | 0.72 | MEN1 (0.31) | ALDH1A1 | |
| SCHEMBL26231913 | 0.72 | LMNA (0.46) | KDM4EALDH1A1HSD17B10FFAR4MRGPRX4 | |
| SCHEMBL31181867 | 0.71 | TSHR (0.36) | CYP2C9AURKATPX2 | |
| SCHEMBL9804225 | 0.70 | EPHX2 (0.32) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677479-B2 | REACTING A HALOGENATED BENZENE COMPOUND WITH ALDEHYDE; SOLVENT EXTRACTION; PURIFICATION | CLARIANT FINANCE LBVI LIMITED (VG) | 2004-01-13 | — | — | US | disclosed |
| US-20030092930-A1 | Substituted fluoroaromatics, process for preparing them and their use | CLARIANT GMBH | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092930-A1 | Substituted fluoroaromatics, process for preparing them and their use | CYP2F1, CYP1A1, CYP4X1 | AKR1C2 993/4885AKR1C1 834/4885KDM4E 1277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.