SCHEMBL6725836

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6721460	0.90	KIF11 (0.57)	KIF11PTGS2PTGS1CA12CA2
	SCHEMBL6732326	0.88	KIF11 (0.52)	KIF11PTGS2PTGS1SOS1
	SCHEMBL6725685	0.87	KIF11 (0.55)	KIF11PTGS2PTGS1CA12CA2
	SCHEMBL6724229	0.86	KIF11 (0.54)	KIF11PTGS2PTGS1CA12CA2
	SCHEMBL6728142	0.86	KIF11 (0.60)	KIF11PTGS2PTGS1CA12CA2
	SCHEMBL6728873	0.85	PTGS2 (0.50)	KIF11PTGS2PTGS1CA12CA2
	SCHEMBL6724255	0.85	KIF11 (0.50)	KIF11PTGS2PTGS1CA12CA2
	SCHEMBL6721595	0.85	KIF11 (0.56)	KIF11PTGS2PTGS1SOS1
	SCHEMBL6728375	0.84	KIF11 (0.58)	KIF11PTGS2PTGS1
	SCHEMBL6725528	0.83	PTGS1 (0.50)	KIF11PTGS2PTGS1CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.