Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578111 | 0.85 | MAPT (0.45) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL4000024 | 0.82 | CHRM1 (0.50) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL4293437 | 0.82 | MAPT (0.52) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL13609827 | 0.77 | MAPT (0.45) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL10491540 | 0.74 | MAPT (0.70) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL4126180 | 0.74 | MAPT (0.70) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL14690094 | 0.74 | NPC1 (0.48) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL9450739 | 0.74 | NPC1 (0.48) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL14690050 | 0.73 | MAPT (0.51) | MAPTNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL4292105 | 0.72 | THRB (0.43) | MAPTNPC1HTTRAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677318-B1 | Cross-linked agent for generation of a long-lasting satiety effect and method for the production of the said | SCHUTTE/REICHEL GBR (DE) | 2004-01-13 | — | — | US | disclosed |