Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ARNT | P27540 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6722875 | 0.91 | PTGS2 (0.43) | PTGS2NR3C2KCNK3ALDH1A1EPAS1 | |
| SCHEMBL6721416 | 0.90 | PTGS2 (0.50) | PTGS2NR3C2USP7KCNN4KCNA5 | |
| SCHEMBL6729318 | 0.90 | PTGS2 (0.43) | PTGS2ALDH1A1BRD4 | |
| SCHEMBL6734977 | 0.88 | PTGS2 (0.42) | PTGS2NR3C2KCNK3ALDH1A1EPAS1 | |
| SCHEMBL6735001 | 0.88 | PTGS2 (0.38) | PTGS2NR3C2KCNK3ALDH1A1EPAS1 | |
| SCHEMBL6730378 | 0.87 | PTGS2 (0.47) | PTGS2ALDH1A1GABRA5BRD4 | |
| SCHEMBL6725376 | 0.86 | PTGS2 (0.46) | PTGS2ALDH1A1BRD4 | |
| SCHEMBL6729521 | 0.86 | PTGS2 (0.46) | PTGS2NR3C2ALDH1A1POLBGABRG2 | |
| SCHEMBL6733277 | 0.86 | PTGS2 (0.58) | PTGS2ALDH1A1BRD4 | |
| SCHEMBL6732167 | 0.85 | PTGS2 (0.39) | PTGS2ALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092552-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | PHARMACIA CORPORATION | 2004-05-13 | — | — | US | disclosed |
| US-20020183362-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | PHARMACIA CORPORATION | 2002-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183362-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | FPR2, FPR1, PTGES2 | PTGS2 5/4885NR3C2 463/4885KCNK3 3305/4885 |
| US-20040092552-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | FPR2, PTGES2, FPR1 | PTGS2 5/4885NR3C2 358/4885KCNK3 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.