Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | HTT | P42858 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26845359 | 0.88 | MEN1 (0.51) | RAB9AHTTMAPTNPSR1MAPK1 | |
| SCHEMBL3934125 | 0.87 | RAB9A (0.38) | RAB9AHTTMAPTNPSR1MAPK1 | |
| SCHEMBL26392086 | 0.87 | RAB9A (0.38) | RAB9AHTTMAPTNPSR1MAPK1 | |
| SCHEMBL3934123 | 0.87 | RAB9A (0.38) | RAB9AHTTMAPTNPSR1MAPK1 | |
| SCHEMBL26845472 | 0.87 | RAB9A (0.42) | RAB9AHTTMAPTNPSR1MAPK1 | |
| Iodide SCHEMBL5918651 | 0.86 | MEN1 (0.38) | RAB9AHTTMAPTNPSR1MAPK1 | |
| SCHEMBL13525403 | 0.86 | KMT2A (0.40) | RAB9AHTTMAPTNPSR1MAPK1 | |
| Iodide SCHEMBL27997113 | 0.86 | RAB9A (0.37) | RAB9AHTTMAPTNPSR1MAPK1 | |
| Iodide SCHEMBL3662105 | 0.85 | MAPT (0.39) | RAB9AHTTMAPTNPSR1MAPK1 | |
| Iodide SCHEMBL17350237 | 0.85 | MAPT (0.39) | RAB9AHTTMAPTNPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012154555-A1 | NANOCOMPOSITIONS FOR MONITORING POLYMERASE CHAIN REACTION (PCR) | THE GENERAL HOSPITAL CORPORATION (US) | 2012-11-15 | — | — | WO | disclosed |
| US-20120121509-A1 | VITAL FLUOROCHROME CONJUGATES AND METHODS OF USE | THE GENERAL HOSPITAL CORPORATION (US) | 2012-05-17 | — | — | US | disclosed |
| WO-2010141833-A2 | VITAL FLUOROCHROME CONJUGATES AND METHODS OF USE | THE GENERAL HOSPITAL CORPORATION (US) | 2010-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120121509-A1 | VITAL FLUOROCHROME CONJUGATES AND METHODS OF USE | CASP3, CASP7, CD47 | RAB9A 3713/4885HTT 3381/4885MAPT 2110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.