Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4770609 | 0.87 | KMT2A (0.47) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| Hydrochloric Acid SCHEMBL4766222 | 0.86 | KMT2A (0.47) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| SCHEMBL4772789 | 0.85 | METAP1 (0.42) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4768653 | 0.83 | CYP1A2 (0.48) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6292095 | 0.82 | KMT2A (0.48) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4766228 | 0.80 | KMT2A (0.49) | ALDH1A1KMT2AMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL4770422 | 0.78 | KMT2A (0.40) | ALDH1A1KDM4EKMT2AMEN1TDP1 | |
| Oxalic Acid SCHEMBL4771110 | 0.78 | SIGMAR1 (0.45) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL6292035 | 0.78 | MAPT (0.45) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| Oxalic Acid SCHEMBL4766826 | 0.77 | KDM4E (0.42) | ALDH1A1KDM4EKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. | 2004-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204421-A1 | Certain 1,3-disubstituted isoquinoline derivatives | MUSK, HTR1A, RYR1 | ALDH1A1 1071/4885KDM4E 1058/4885KMT2A 1300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.