Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | LIPC | P11150 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 8/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.34 |
| ▸ | RORC | P51449 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1725449 | 0.75 | PTGES (0.47) | CNR2PTGESSCN9A | |
| SCHEMBL1725448 | 0.75 | PTGES (0.47) | CNR2PTGESSCN9A | |
| SCHEMBL671609 | 0.74 | KDM4E (0.36) | CNR2 | |
| SCHEMBL10170049 | 0.74 | PTGES (0.48) | CNR2PTGESSCN9A | |
| SCHEMBL11970148 | 0.74 | PTGES (0.48) | CNR2PTGESSCN9A | |
| SCHEMBL10170051 | 0.66 | MLNR (0.49) | CNR2PTGES | |
| SCHEMBL11970126 | 0.66 | MLNR (0.49) | CNR2PTGES | |
| SCHEMBL1671952 | 0.66 | ALDH1A1 (0.51) | CNR2PTGESSCN9A | |
| SCHEMBL1671955 | 0.66 | ALDH1A1 (0.51) | CNR2PTGESSCN9A | |
| SCHEMBL11951408 | 0.65 | PRKCI (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606036-A1 | NEW COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012022793-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-23 | — | — | WO | disclosed |