Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | VEGFA | P15692 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30575111 | 0.90 | L3MBTL1 (0.43) | L3MBTL1PTGDR2RAPGEF4HTTKMT2A | |
| SCHEMBL24262373 | 0.90 | L3MBTL1 (0.43) | L3MBTL1PTGDR2RAPGEF4HTTKMT2A | |
| SCHEMBL29247903 | 0.87 | PTGDR2 (0.47) | L3MBTL1ALOX5PTGDR2RAPGEF4HTT | |
| SCHEMBL13494114 | 0.82 | L3MBTL1 (0.50) | L3MBTL1RAPGEF4HTTPOLBALDH3A1 | |
| SCHEMBL5264564 | 0.79 | L3MBTL1 (0.50) | L3MBTL1PTGDR2RAPGEF4HTTMEN1 | |
| SCHEMBL3384664 | 0.78 | L3MBTL1 (0.44) | L3MBTL1ALOX5PTGDR2RAPGEF4MMP2 | |
| SCHEMBL5411086 | 0.77 | L3MBTL1 (0.50) | L3MBTL1RAPGEF4HTTPOLBALDH3A1 | |
| SCHEMBL260617 | 0.77 | L3MBTL1 (0.55) | L3MBTL1RAPGEF4HTTPOLBALDH3A1 | |
| SCHEMBL13769391 | 0.76 | L3MBTL1 (0.46) | L3MBTL1PTGDR2RAPGEF4MEN1KMT2A | |
| SCHEMBL4068111 | 0.76 | L3MBTL1 (0.49) | L3MBTL1PTGDR2RAPGEF4HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183248-B2 | Substituted pyrrolo[2,3-d]pyrimidines and compositions as protein kinase inhibitors | IRM LLC (BM) | 2012-05-22 | — | — | US | disclosed |
| US-20090118273-A1 | Compounds and Compositions as Protein Kinase Inhibitors | IRM LLC (BM) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118273-A1 | Compounds and Compositions as Protein Kinase Inhibitors | SRC, FYN, SYK | L3MBTL1 4367/4885ALOX5 4309/4885PTGDR2 2188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.