Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24262373 | 1.00 | L3MBTL1 (0.43) | L3MBTL1POLBKDM4EMAPK1HSD17B10 | |
| SCHEMBL6726762 | 0.90 | L3MBTL1 (0.44) | L3MBTL1POLBKMT2AALDH1A1RAPGEF4 | |
| SCHEMBL29247903 | 0.86 | PTGDR2 (0.47) | L3MBTL1POLBKDM4ERAPGEF4HTT | |
| SCHEMBL13494114 | 0.84 | L3MBTL1 (0.50) | L3MBTL1POLBTSHRALDH1A1RAPGEF4 | |
| SCHEMBL13769391 | 0.82 | L3MBTL1 (0.46) | L3MBTL1KDM4EKMT2ALMNATSHR | |
| SCHEMBL24262374 | 0.80 | L3MBTL1 (0.43) | L3MBTL1POLBKDM4EMAPK1HSD17B10 | |
| SCHEMBL4067920 | 0.80 | L3MBTL1 (0.44) | L3MBTL1POLBKDM4EKMT2ALMNA | |
| SCHEMBL5264564 | 0.78 | L3MBTL1 (0.50) | L3MBTL1POLBKDM4EKMT2ATSHR | |
| SCHEMBL3384671 | 0.78 | L3MBTL1 (0.41) | L3MBTL1POLBKDM4EMAPK1HSD17B10 | |
| SCHEMBL24262406 | 0.77 | RECQL (0.44) | L3MBTL1POLBKDM4EMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317946-A | Processes and intermediates for the preparation of baratinib | 因赛特公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-117043152-A | Methods and intermediates for preparing JAK1 inhibitors | 因赛特公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116761792-A | Methods and intermediates for preparing JAK inhibitors | 因赛特公司 | 2023-09-15 | — | — | CN | disclosed |