Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | TACR1 | P25103 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | RORA | P35398 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.49 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL6722850 | 0.94 | RAB9A (0.52) | RAB9ANPC1TACR1EPHX2MAPT | |
| SCHEMBL6715643 | 0.84 | ALDH1A1 (0.67) | RAB9ATACR1MAPTTP53POLB | |
| SCHEMBL6715648 | 0.84 | ALDH1A1 (0.67) | RAB9ATACR1MAPTTP53POLB | |
| SCHEMBL19074543 | 0.84 | POLB (0.66) | RAB9ANPC1EPHX2MAPTTP53 | |
| SCHEMBL4982071 | 0.84 | POLB (0.66) | RAB9ANPC1EPHX2MAPTTP53 | |
| SCHEMBL29521458 | 0.83 | RAB9A (0.59) | RAB9ANPC1TACR1EPHX2MAPT | |
| SCHEMBL5576509 | 0.83 | KLK7 (0.56) | RAB9ANPC1POLBROCK2ROCK1 | |
| SCHEMBL5576504 | 0.83 | KLK7 (0.56) | RAB9ANPC1POLBROCK2ROCK1 | |
| SCHEMBL23611208 | 0.82 | ROCK2 (0.56) | MAPTPOLBROCK2ROCK1MEN1 | |
| SCHEMBL23611205 | 0.82 | ROCK2 (0.56) | MAPTPOLBROCK2ROCK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152741-A1 | Arylglycine derivatives and their use as glycine transport inhibitors | NPS ALLELIX CORPORATION (CA) | 2004-08-05 | — | — | US | disclosed |
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152741-A1 | Arylglycine derivatives and their use as glycine transport inhibitors | SLC1A2, SLC1A1, SLC7A11 | RAB9A 1608/4885NPC1 119/4885TACR1 749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.