Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 5/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675407 | 0.86 | POLB (0.40) | POLBALPLALPGCYP1A2SRR | |
| SCHEMBL673685 | 0.85 | POLB (0.42) | POLBALPLALPGCYP1A2SRR | |
| SCHEMBL675637 | 0.85 | POLB (0.42) | POLBALPLALPGCYP1A2SRR | |
| SCHEMBL673481 | 0.83 | POLB (0.40) | POLBALPLALPGCYP1A2SRR | |
| SCHEMBL674471 | 0.81 | POLB (0.39) | POLBALPLALPGCYP1A2PPARG | |
| SCHEMBL673675 | 0.70 | CYP1A2 (0.48) | CYP1A2SRRSMN1; SMN2HIF1AALPI | |
| SCHEMBL6674070 | 0.69 | ALPL (0.41) | POLBALPLALPGCYP1A2SRR | |
| SCHEMBL11169147 | 0.68 | SMN1; SMN2 (0.43) | POLBCYP1A2SRRSMN1; SMN2HIF1A | |
| SCHEMBL674366 | 0.66 | HDAC3 (0.46) | SMN1; SMN2HIF1AFDPSMAPTTDP1 | |
| SCHEMBL672705 | 0.64 | PTPN1 (0.35) | SMN1; SMN2HIF1AMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10131722-B2 | Method for preparing terminal-modified conjugated diene polymer, terminal-modified conjugated diene polymer, rubber composition and tire | BRIDGESTONE CORPORATION (JP) | 2018-11-20 | — | — | US | disclosed |
| US-20170275400-A1 | METHOD FOR PREPARING TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, TERMINAL-MODIFIED CONJUGATED DIENE POLYMER, RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2017-09-28 | — | — | US | disclosed |
| EP-3184554-A1 | METHOD FOR MANUFACTURING CONJUGATED DIENE POLYMER WITH MODIFIED END, CONJUGATED DIENE POLYMER WITH MODIFIED END, RUBBER COMPOSITION, AND TIRE | Bridgestone Corporation (JP) | 2017-06-28 | — | — | EP | disclosed |
| US-7968652-B2 | Modified conjugated diene copolymer, rubber compositions and tires | BRIDGESTONE CORPORATION (JP) | 2011-06-28 | — | — | US | disclosed |
| US-20100160530-A1 | RUBBER COMPOSITION CONTAINING MODIFIED POLYBUTADIENE RUBBER AND TIRE | BRIDGESTRONE CORPORATION (JP) | 2010-06-24 | — | — | US | disclosed |
| US-20090292043-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | BRIDGESTONE CORPORATION (JP) | 2009-11-26 | — | — | US | disclosed |
| EP-1975200-A1 | RUBBER COMPOSITION CONTAINING MODIFIED POLYBUTADIENE RUBBER AND TIRE | Bridgestone Corporation (JP) | 2008-10-01 | — | — | EP | disclosed |
| EP-1873168-A1 | MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES | Bridgestone Corporation (JP) | 2008-01-02 | — | — | EP | disclosed |