Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG known ✓ | P37231 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 6/20 | 0.38 |
| ▸ | MMP9 | P14780 | 5/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17512884 | 0.78 | CYP2C19 (0.36) | ALPLPOLBALPGMMP2MMP9 | |
| SCHEMBL18342943 | 0.78 | CYP1A2 (0.43) | MMP2MMP9ADAMTS4CYP1A2SRR | |
| SCHEMBL8356358 | 0.77 | ALDH1A1 (0.33) | ALPLPOLBALPGMMP9ALDH1A1 | |
| SCHEMBL7782717 | 0.76 | ALDH1A1 (0.39) | POLBALDH1A1MAPTCYP1A2SMN1; SMN2 | |
| SCHEMBL8644485 | 0.73 | HDAC3 (0.41) | MMP2MMP9ALDH1A1MAPT | |
| SCHEMBL675407 | 0.69 | POLB (0.40) | ALPLPOLBALPGMAPTCYP1A2 | |
| SCHEMBL672704 | 0.69 | POLB (0.40) | ALPLPOLBALPGMAPTCYP1A2 | |
| SCHEMBL675637 | 0.68 | POLB (0.42) | ALPLPOLBALPGMAPTGAA | |
| SCHEMBL673685 | 0.68 | POLB (0.42) | ALPLPOLBALPGALDH1A1MAPT | |
| SCHEMBL21269475 | 0.66 | ALPL (0.46) | ALPLPOLBALPGCYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0930530-B1 | Curtain coating apparatus | FUJI PHOTO FILM CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| EP-0457153-B1 | Method for processing a silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 2002-09-18 | — | — | EP | disclosed |
| US-6287384-B2 | Curtain coating method and apparatus for photographic printing paper | FUJI PHOTO FILM CO., LTD. (JP) | 2001-09-11 | — | — | US | disclosed |
| EP-0930530-A2 | Curtain coating method and apparatus for photographic printing paper | Fuji Photo Film Co., Ltd. (JP) | 1999-07-21 | — | — | EP | disclosed |
| EP-0567118-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1998-09-16 | — | — | EP | disclosed |
| EP-0460550-B1 | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1997-08-06 | — | — | EP | disclosed |
| EP-0456163-B1 | Silver halide photographic materials | FUJI PHOTO FILM CO LTD (JP) | 1997-08-06 | — | — | EP | disclosed |
| EP-0404091-A2 | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |