Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18874266 | 1.00 | KDM1A (0.36) | KDM1AHDAC3HDAC1HDAC2HTR2C | |
| SCHEMBL6727873 | 0.88 | TAAR1 (0.41) | HDAC1HDAC2HTR2CPGRGRM2 | |
| SCHEMBL18874001 | 0.88 | TAAR1 (0.41) | HDAC1HDAC2HTR2CPGRGRM2 | |
| SCHEMBL10273076 | 0.81 | GRM2 (0.33) | HDAC3HDAC1HDAC2GRM2 | |
| SCHEMBL10266665 | 0.79 | MAPK1 (0.38) | KDM1A | |
| SCHEMBL2120447 | 0.79 | MAPK1 (0.38) | KDM1A | |
| SCHEMBL18874242 | 0.75 | HSD17B1 (0.34) | HDAC3HDAC1HDAC2PGR | |
| SCHEMBL6727346 | 0.75 | HSD17B1 (0.34) | HDAC3HDAC1HDAC2PGR | |
| SCHEMBL6727919 | 0.75 | L3MBTL1 (0.36) | HDAC3HDAC1HDAC2KLKB1 | |
| SCHEMBL18874115 | 0.75 | L3MBTL1 (0.36) | HDAC3HDAC1HDAC2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173755-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2017-05-17 | — | — | EP | disclosed |
| US-8940913-B2 | Herbicides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-8940913-B2 | Herbicides | SYNGENTA CROP PROTECTION, LLC (US) | 2015-01-27 | — | — | US | disclosed |
| US-8835657-B2 | Cyclopentanedione compounds and their use as insecticides, acaricides and/or fungicides | BAYER CROPSCIENCE AG (DE) | 2014-09-16 | — | — | US | disclosed |
| US-8835657-B2 | Cyclopentanedione compounds and their use as insecticides, acaricides and/or fungicides | BAYER CROPSCIENCE AG (DE) | 2014-09-16 | — | — | US | disclosed |
| US-20120142529-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120142529-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120123129-A1 | Cyclopentanedione Compounds and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| US-20120123129-A1 | Cyclopentanedione Compounds and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| WO-2010127797-A2 | CYCLOPENTANEDIONE COMPOUNDS AND THEIR USE AS INSECTICIDES, ACARICIDES AND/OR FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-11-11 | — | — | WO | disclosed |
| WO-2009019015-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123129-A1 | Cyclopentanedione Compounds and Their Use as Insecticides, Acaricides and/or Fungicides | CYP51A1, CYP1B1, CBR3 | KDM1A 1928/4885HDAC3 531/4885HDAC1 993/4885 |
| US-20120142529-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | KDM1A 223/4885HDAC3 946/4885HDAC1 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.