Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6727385 | 0.81 | KDM1A (0.36) | GRM2HDAC3HDAC1HDAC2 | |
| SCHEMBL18874266 | 0.81 | KDM1A (0.36) | GRM2HDAC3HDAC1HDAC2 | |
| SCHEMBL18874242 | 0.70 | HSD17B1 (0.34) | HDAC3HDAC1HDAC2 | |
| SCHEMBL6727346 | 0.70 | HSD17B1 (0.34) | HDAC3HDAC1HDAC2 | |
| SCHEMBL18874001 | 0.69 | TAAR1 (0.41) | GRM2HDAC1HDAC2 | |
| SCHEMBL6727873 | 0.69 | TAAR1 (0.41) | GRM2HDAC1HDAC2 | |
| SCHEMBL18874115 | 0.62 | L3MBTL1 (0.36) | HDAC3HDAC1HDAC2 | |
| SCHEMBL6727919 | 0.62 | L3MBTL1 (0.36) | HDAC3HDAC1HDAC2 | |
| SCHEMBL18873867 | 0.61 | L3MBTL1 (0.33) | — | |
| SCHEMBL18874265 | 0.61 | PGR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142529-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142529-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | GRM2 23/4885HDAC3 946/4885HDAC1 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.