Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6728049 | 0.86 | MEN1 (0.48) | MAPTLTB4RKMT2AMEN1ALDH1A1 | |
| SCHEMBL6728569 | 0.85 | LTB4R (0.47) | MAPTLTB4RKMT2AMEN1ALDH1A1 | |
| SCHEMBL4804158 | 0.78 | RXRA (0.53) | KMT2AMEN1VCPSMN1; SMN2MAPK1 | |
| SCHEMBL6727777 | 0.77 | POLB (0.56) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL733458 | 0.76 | HPGD (0.58) | LTB4RKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL4802532 | 0.75 | CTRC (0.55) | MAPTLTB4RKMT2AMEN1KDM4E | |
| SCHEMBL15997352 | 0.75 | MAOB (0.75) | MAPTKMT2AMEN1KDM4EPOLB | |
| SCHEMBL15282195 | 0.75 | MAOB (0.75) | MAPTKMT2AMEN1KDM4EPOLB | |
| SCHEMBL28489642 | 0.74 | MEN1 (0.60) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL6731942 | 0.74 | MEN1 (0.60) | MAPTKMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110757-A1 | Flt-1 ligands and their uses in the treatment of diseases regulatable by angiogenesis | ARRHENIUS THOMAS (US) | 2004-06-10 | — | — | US | disclosed |
| EP-1370250-A2 | FLT-1 LIGANDS AND THEIR USES IN THE TREATMENT OF DISEASES REGULATABLE BY ANGIOGENESIS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002076438-A2 | FLT-1 LIGANDS AND THEIR USES IN THE TREATMENT OF DISEASES REGULATABLE BY ANGIOGENESIS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110757-A1 | Flt-1 ligands and their uses in the treatment of diseases regulatable by angiogenesis | FLT1, FLT4, TEK | MAPT 2310/4885LTB4R 677/4885KMT2A 2223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.