Diethylcarbamazine

Diethylcarbamazine

SCHEMBL67289

CCN(CC)C(=O)N1CCN(C)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 1.00
KDM4E B2RXH2 4/20 0.68
ALDH1A1 P00352 3/20 0.68
TSHR P16473 2/20 0.68
LMNA P02545 1/20 0.68
MAPT P10636 1/20 0.68
ALOX15 P16050 1/20 0.68
POLB P06746 2/20 0.59
TDP1 Q9NUW8 3/20 0.48
CYP1A2 P05177 1/20 0.48
KMT2A Q03164 1/20 0.46
RYR2 Q92736 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
KDM4C Q9H3R0 1/20 0.41
HTT P42858 1/20 0.40
PHGDH O43175 1/20 0.40
MGLL Q99685 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethylcarbamazine SCHEMBL1819685 1.00 HTR1A (1.00) HTR1AKDM4EALDH1A1TSHRLMNA
Diethylcarbamazine SCHEMBL10412471 0.98 HTR1A (0.96) HTR1AKDM4EALDH1A1TSHRLMNA
Diethylcarbamazine SCHEMBL2719699 0.96 HTR1A (0.92) HTR1AKDM4EALDH1A1TSHRLMNA
SCHEMBL11096507 0.94 HTR1A (0.89) HTR1AKDM4EALDH1A1TSHRLMNA
Diethylcarbamazine SCHEMBL27894397 0.91 HTR1A (0.82) HTR1AKDM4EALDH1A1TSHRLMNA
Diethylcarbamazine SCHEMBL28938729 0.89 HTR1A (0.79) HTR1AKDM4EALDH1A1TSHRLMNA
Diethylcarbamazine SCHEMBL2319899 0.89 HTR1A (0.79) HTR1AKDM4EALDH1A1TSHRLMNA
SCHEMBL11506548 0.85 HTR1A (0.74) HTR1AKDM4EALDH1A1TSHRLMNA
SCHEMBL21140593 0.82 HTR1A (0.69) HTR1AKDM4EALDH1A1TSHRLMNA
Diethylcarbamazine SCHEMBL37736 0.82 KDM4E (1.00) HTR1AKDM4EALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6636 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4736841-A1 A MUCOADHESIVE LAYER FOR BUCCAL ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT IQ medical GmbH (DE) 2026-05-06 EP claimed
US-20260102373-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2026-04-16 US claimed
US-12573605-B2 Dry electrode manufacture with composite binder LICAP TECHNOLOGIES, INC. (US) 2026-03-10 US claimed
US-20260000769-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2026-01-01 US claimed
US-20250352510-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2025-11-20 US claimed
US-12465623-B2 Use of parasites and extracellular vesicles obtained from parasites in cancer treatment YEDITEPE UNIVERSITESI (TR) 2025-11-11 US claimed
US-20250325671-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2025-10-23 US claimed
EP-4633617-A1 USE OF BORON FOR THE TREATMENT OF LEISHMANIASIS DISEASE Yeditepe Universitesi (TR) 2025-10-22 EP claimed
EP-4633643-A1 USE OF BORON FOR THE TREATMENT OF LEISHMANIASIS DISEASE OF NEURONAL ORIGIN Yeditepe Universitesi (TR) 2025-10-22 EP claimed
US-20250312461-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2025-10-09 US claimed
US-4736024-A Process for preparing salt of hyaluronic acid with a pharmaceutically active substance FIDIA, S.P.A. (IT) 1988-04-05 US claimed
US-4702914-A Veterinary-sauce prophylactic RYAN HILLARY A 1987-10-27 US claimed
EP-0197718-A2 New medicaments for topical use FIDIA S.p.A. (IT) 1986-10-15 EP claimed
US-4578268-A ION EXCHANGE RESINS OF SULFONATED DIVINYLBENZENE-STYRENE COPOLYMER; FEEDS AMERICAN CYANAMID COMPANY (US) 1986-03-25 US claimed
US-4442086-A Diethylcarbamazine resinate and styrylpyridinium resinate-diethylcarbamazine resinate edible anthelmintic tablets for companion animals AMERICAN CYANAMID COMPANY (US) 1984-04-10 US claimed
US-4431478-A Etching agent for polyimide type resins and process for etching polyimide type resins with the same SUMITOMO BAKELITE CO. LTD. (JP) 1984-02-14 US claimed
US-4389393-A Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose FOREST LABORATORIES, INC. (US) 1983-06-21 US claimed
US-4352891-A ION EXCHANGING AMERICAN CYANAMID CO. (US) 1982-10-05 US claimed
US-4147785-A Method for the treatment of onchocerciasis Dobbie, Graham J. (US) 1979-04-03 US claimed
US-3956330-A N,N-diethyl-4-methyl-1-pi-perazinecarboxamide pamoate AMERICAN CYANAMID COMPANY (US) 1976-05-11 US claimed