Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6722957 | 0.93 | PTGS2 (0.50) | PTGS2PTGS1ESR1ESR2FFAR4 | |
| SCHEMBL6722747 | 0.90 | PTGS2 (0.46) | PTGS2PTGS1ESR1ESR2FFAR4 | |
| SCHEMBL6729359 | 0.89 | PTGS2 (0.46) | PTGS2PTGS1ESR1ESR2FFAR4 | |
| SCHEMBL6722930 | 0.89 | PTGS2 (0.54) | PTGS2PTGS1ESR1ESR2FFAR4 | |
| SCHEMBL6721417 | 0.89 | PTGS2 (0.50) | PTGS2PTGS1ESR1ESR2F2 | |
| SCHEMBL6723661 | 0.88 | PTGS2 (0.46) | PTGS2PTGS1ESR1ESR2FFAR4 | |
| SCHEMBL6726040 | 0.87 | PTGS2 (0.48) | PTGS2PTGS1ESR1ESR2F2 | |
| SCHEMBL6722713 | 0.87 | PTGS2 (0.60) | PTGS2PTGS1ESR1ESR2FFAR4 | |
| SCHEMBL6721592 | 0.87 | PTGS2 (0.48) | PTGS2PTGS1ESR1ESR2FFAR4 | |
| SCHEMBL6718530 | 0.86 | PTGS2 (0.59) | PTGS2PTGS1ESR1ESR2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092552-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | PHARMACIA CORPORATION | 2004-05-13 | — | — | US | disclosed |
| US-20020183362-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | PHARMACIA CORPORATION | 2002-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183362-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | FPR2, FPR1, PTGES2 | PTGS2 5/4885PTGS1 4/4885ESR1 1770/4885 |
| US-20040092552-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | FPR2, PTGES2, FPR1 | PTGS2 5/4885PTGS1 4/4885ESR1 1900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.