Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 12/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.34 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6728858 | 0.91 | RPS6KA3 (0.43) | RPS6KA3PTGS2PTGS1TP53CYP3A4 | |
| SCHEMBL6725948 | 0.91 | RPS6KA3 (0.46) | RPS6KA3PTGS2RPS6KA2RPS6KA1ALOX5AP | |
| SCHEMBL6722648 | 0.90 | RPS6KA3 (0.45) | RPS6KA3PTGS2PTGS1RPS6KA2RPS6KA1 | |
| SCHEMBL6730117 | 0.90 | RPS6KA3 (0.41) | RPS6KA3PTGS2TP53CYP3A4MAPT | |
| SCHEMBL6725964 | 0.87 | RPS6KA3 (0.45) | RPS6KA3PTGS2PTGS1RPS6KA2RPS6KA1 | |
| SCHEMBL6725468 | 0.87 | RPS6KA3 (0.46) | RPS6KA3PTGS2TP53CYP3A4MAPT | |
| SCHEMBL6718429 | 0.86 | PTGS2 (0.44) | RPS6KA3PTGS2PTGS1RPS6KA2RPS6KA1 | |
| SCHEMBL6723317 | 0.86 | RPS6KA3 (0.59) | RPS6KA3PTGS2PTGS1RPS6KA2RPS6KA1 | |
| SCHEMBL6729507 | 0.85 | RPS6KA3 (0.51) | RPS6KA3PTGS2RPS6KA2RPS6KA1ALOX5AP | |
| SCHEMBL6730633 | 0.85 | RPS6KA3 (0.44) | RPS6KA3PTGS2TP53CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040092552-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | PHARMACIA CORPORATION | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092552-A1 | 2-Fluorobenzenesulfonyl compounds for the treatment of inflammation | FPR2, PTGES2, FPR1 | RPS6KA3 972/4885PTGS2 5/4885PTGS1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.